Up to 40% off Cyber Offers!*

New U.S. Tariffs. Same Prices. Read our statement here.

Windows 11 Security Package Learn more

Implant Solutions World Summit 2026 Register now

The bioactive method that goes the extra mile in root canal sealing 

Prefer the bioactive method of root canal sealing? ProRoot Bio Sealer goes the extra mile with higher bioactive cement content compared to other bioceramic sealers,1 high clinical success rates,2 and easy handling with minimal waste.3

ProRoot Bio Sealer is a ready-to-use, premixed, injectable, and resin-free material that facilitates direct application into the root canals. It is designed for cold, warm, and carrier-based techniques.4 

Buy

Why choose ProRoot Bio Sealer?

Suitable for all obturation techniques

Delivers consistent performance across cold, warm, and carrier-based methods4 —plus it’s retreatable5 and non-staining.8

Higher bioactive cement content

Promotes hydroxyapatite formation6 and leads to a high pH value.7

Easy handling with minimal waste

The ProRoot Flex Tip enables precise application into complex canals with up to 49% less waste per tip.3

High clinical success rates

Demonstrated very high short-term healing rates, more stable radiographic visibility over time and comparable low post-op sensitivity compared to leading bioceramic sealer.2

Connected solutions for bioactive endodontics

SmartLite® Pro EndoActivator

Enhance canal cleanliness and sealer integration by pairing ProRoot Bio Sealer with the SmartLite Pro EndoActivator for optimized irrigation.
Conform Fit® Gutta-Percha

Pair ProRoot with Conform Fit gutta-percha points for a snug apical fit and an accurate tug back that you can feel.

How to

Step 1:

Perform final irrigation with distilled water and dry the root canal using paper points. Moisture is required for setting.

Step 2:

Attach the tip to the syringe. If used intraorally, cover with a disposable sleeve to reduce contamination. Test flow by dispensing a small amount onto a pad before use.

Step 3:

Insert the tip into the canal to the desired depth, taking care to not insert the end past the middle third of the root canal. Avoid forcing or sealing the tip against canal walls.

Step 4:

Apply gentle, steady pressure to the syringe plunger with a constant outward movement from the canal as the material is injected.

Step 5:

Proceed with your preferred obturation technique.

Step 6:

Clean and disinfect the syringe per protocol. To prevent hardening, recap immediately and store in the protective aluminum packaging provided. Store at room temperature.

Unlock efficiency with ONE DS

ONE DS is a simple but comprehensive loyalty program that provides value-add benefits to help advance your dental practice with confidence. Start earning points today!
Sign up for ONE DS
Learn more

Related products

AH Plus Ribbon
Learn more
Gutta-Smart
Learn more
SDR flow+
Learn more
GuttaCore Obturators
Learn more

Frequently asked questions

It contains a higher percentage of bioactive cement content,1 which contributes to a high pH7 and promotes hydroxyapatite formation.6

Yes. It’s suitable for cold, warm, and carrier-based techniques,4 offering flexibility for any obutration approach.

Yes. The included ProRoot Flex Tips, which you can optionally bend to an angle you prefer, are designed for precision placement with excellent flowability—even in curved or irregular canals.

Only 0.087 grams, which is up to 49% less waste per tip3 compared to other bioceramic applicators, making it efficient and cost-conscious.

No. It’s a non-staining formula8 and maintains more stable radiographic visibility over time compared to leading bioceramic sealer,2 aiding in long-term monitoring.

ProRoot BioSealer is easy to retreat,5 making it a good choice for successful and time efficient retreatment procedures.

Explore Endodontics

Downloads

ProRoot® Bio Sealer | Fact File | EN
This fact file focuses on the physico-chemical properties of the ProRoot ® Bio Sealer, the biological responses and some clinical aspects, providing a comprehensive understanding of its potential in root canal treatment.
1 MB
Download
ProRoot® Bio Sealer | Technique Guide | EN
Step-by-step instructions for the bioceramic endo sealer ProRoot Bio Sealer
53 MB
Download

For instructions for use, safety data sheets, eMDR documents and more, visit our Download Center.

Go to Download Centre

What dentists say about ProRoot Bio Sealer

"ProRoot Bio Sealer has excellent viscosity, allowing me to control placement. It flows into microanatomy and canal irregularities when present. The obturation pops off the screen, giving the postoperative image a dense look with no voids. When a bioceramic sealer is the best alternative, ProRoot Bio Sealer will be my choice."

David J. Landwehr DDS, MS Capital Endodontics, Madison, WI

Contact us
Get in touch

1. Based on crystalline portion evaluated by XRD analysis comparing different bioceramic sealers (cf. chart). Internal data on file. For more information on non-published data, contact Consumables-Data-Requests@dentsplysirona.com

2. Randomized controlled ongoing clinical trial ( >450 follow up cases) comparing bioceramic sealers with AH Plus resin-based sealer, Gustavo De-Deus, University of Rio de Janeiro. External data on file. 

3. Tip waste analysis of different bioceramic sealer tips. Internal data on file. For more information on non-published data, contact Consumables-Data-Requests@dentsplysirona.com

4.In vivo case study comparing handling of bioceramic sealers using warm obturation technique, Walsh. External data on file.  

5. Carrillo, et al. Retrievability of calcium silicate-based root canal  sealers during retreatment: an ex vivo study. Journal of Endodontics, 48(6), 781–786, February 2022. 

6. SEM analysis 2025, DS funded, University of Zurich, external data on file.

7. In vitro pH study, demonstrated pH level of up to 11. Internal data on file. For more information on non-published data, contact Consumables-Data-Requests@dentsplysirona.com

8. ProRoot® Bio Sealer does not contain bismuth oxide which is responsible for staining